Translational Informatics Research and Innovation (TIRI) Lab

From Personal Health Insights to Clinical Use to Public Value


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About


People

We are a collaborative research group in Medicine and Biomedical Engineering at Johns Hopkins University.

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Research

Our research draws from biomedical informatics and the related field of biomedical data science to address challenges to translating discoveries into practice.

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Projects

We pursue projects that address the challenge of how to incorporate technology and digital approaches into research and clinical practices.

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Join Us

We are looking for passionate new PhD students, Master and Bachelor students to join the team.

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News and Announcements

May 30, 2026

Congratulations to Dr. Nguyen and Dr. Rattsev!

Michelle Nguyen and Ilia Rattsev both successfully defended their dissertations and earned a PhD in Biomedical Engineering from The Johns Hopkins University School of Medicine! Nguyen completed NIH pre-doctoral training in computational medicine and in clinical research, and her dissertation is titled "Modern Tools for Stakeholder-aligned Family Health History Information Extraction and Data Collection." Rattsev was research program assistant in ICM prior to starting the BME PhD program, and his dissertation is titled "A Mechanistic Modeling Framework for Pharmacogenomics-Informed Predication of Bone Toxicity." Congratulations to them both on this major achievement!

May 18, 2026

Kevin Gorman receives Paper Award!

First author Kevin Gorman was selected for the Clinical Research Informatics Distinguished Paper Award! Our conference paper titled "Use of Family Relationships in Commercial Claims Data to Characterize Clinical Events of Patients with BRCA1/2 Cascade Testing" was presented in the TRI39 Cancer Informatics - From Bench to Bedside session on Thursday May 21 at the Amplify Informatics Conference held in Denver, CO.

April 23, 2026

Lab representation at JH inHealth Precision Medicine Symposium

Tamisha Segbefia and Chloe Sheen presented at the 2026 JH inHealth Precision Medicine Symposium Poster Session on April 23, 2026.

April 20, 2026

Columbia seminar presentation

Taylor had the honor of delivering a presentation on "Advancing Guideline-Directed Genomic Medicine with Real-World Evidence" at the Columbia University Department of Biomedical Informatics Biomedical Informatics Seminar Series.

March 10, 2026

Paper published in BioData Mining

Our collaborative work titled A multi-metric evaluation of readability in psychiatric discharge summaries was published in BioData Mining.

Febuary 20, 2026

Lab representation at JH DOM/WSE Research Retreat

Kamryn Chan, Kevin Gorman, Nidhi Soley, Tamisha Segbefia, and Chloe Sheen presented at the 2026 Department of Medicine & Whiting School of Engineering Research Retreat Poster Session on February 20, 2026.

Feburary 18, 2026

Paper published in CTS

Our article titled A Framework to Quantify Disparities in Pharmacogenomic Treatment Concordance and Drug Response Outcomes was published in Clinical and Translational Science.

Feburary 6, 2026

Paper published in JAMIA and highlighted on BME Research Hub

Our collaborative work titled Assessing genetic counseling efficiency with natural language processing was published in Journal of the American Medical Informatics Association. It was recently highlighted on the BME Research Hub page here.

January 27, 2026

Study featured on All of Us Research Highlights

Our study to help personalize pain treatment after surgery was featured on All of Us Research Highlights here.

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