Translational Informatics Research and Innovation (TIRI) Lab

From Personal Health Insights to Clinical Use to Public Value


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About


People

We are a collaborative research group in Medicine and Biomedical Engineering at Johns Hopkins University.

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Research

Our research draws from biomedical informatics and the related field of biomedical data science to address challenges to translating discoveries into practice.

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Projects

We pursue projects that address the challenge of how to incorporate technology and digital approaches into research and clinical practices.

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We are looking for passionate new PhD students, Master and Bachelor students to join the team.

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News and Announcements

Feburary 6, 2026

Paper published in JAMIA and highlighted on BME Research Hub

Our article titled Assessing genetic counseling efficiency with natural language processing was published in Journal of the American Medical Informatics Association. It was recently highlighted on the BME Research Hub page here.

January 27, 2026

Study featured on All of Us Research Highlights

Our study to help personalize pain treatment after surgery was featured on All of Us Research Highlights here.

December 2, 2025

Lab representation at NeurIPS 2025

Nidhi Soley had a workshop paper titled AttentiveGRUAE, An Attention-Based GRU Autoencoder for Temporal Clustering and Behavioral Characterization of Depression from Wearable Data at the 2025 Conference on Neural Information Processing Systems held December 2–7 in San Diego, California.

September 12, 2025

2025 PGRN Scientific Meeting in collaboration with ClinPGx

Taylor was thankful for the opportunity to participate on a panel titled "Advancing Pharmacogenomics Through Biobanks, Real-World Data, and Clinical Implementation" at the Pharmacogenomics Global Research Network (PGRN) 2025 Scientific Meeting in collaboration with ClinPGx. The meeting was held at University of Montana Sep 10-12th, 2025. Taylor discussed NIMHD-funded work on "Assessing real-world implications of genome-guided prescribing."

September 5, 2025

Congratulations to Ilia Rattsev!

Ilia Rattsev was selected for the Quantitative Systems Pharmacology SIG award! He will be recognized during the SIG lunch session at The American Conference on Pharmacometrics (ACoP) that will be held from Oct 18-21, 2025 in Aurora, Colorado. His presentation was titled "Evaluating the impact of pharmacogenomic variants on aromatase inhibitor-induced bone toxicity using a QSP model of bone remodeling."

August 9, 2025

Paper published in Scientific Reports

Our article titled Unveiling social determinants of health impact on adverse pregnancy outcomes through natural language processing was published in Scientific Reports.

July 10, 2025

Congratulations to Nidhi Soley!

Nidhi Soley was selected for the JHU BME Distinguished Teaching Assistant award for her outstanding performance during the academic year 2024-2025! She was lead TA for Precision Care Medicine I-II (BME 580.680-881) offered Fall 2024 and Spring 2025.

June 1, 2025

Congratulations to Bhavik Agarwal and Jash Shah!

Bhavik Agarwal completed his MS in Computer Science and his thesis titled “Design and Evaluation of GPT and RAG-Based QA Systems for Genomic and Pharmacogenomic Patient Queries.” He has joined MasterControl as an AI/ML Research Scientist. Jash Shah completed his MS in Computer Science and has joined ServiceNow as a Machine Learning Engineer. He has contributed to a lab project under way automating the review and identification of high-impact genomic medicine implementation research articles. Agarwal and Shah have also contributed to work with other lab members using LLMs to generate synthetic drug-related patient portal messages.

May 29, 2025

Paper published in Scientific Reports and highlighted at ACM-BCB!

Our article titled Relapse prediction using wearable data through convolutional autoencoders and clustering for patients with psychotic disorders was published in Scientific Reports. April Yan was also selected to give an oral presentation on this paper as part of the Highlight Track at the ACM Conference on Bioinformatics, Computational Biology, and Health Informatics (ACM-BCB 2025), held October 12–15, 2025, in Philadelphia, Pennsylvania.

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